2-quinolinylmethyl chloride
2-(Chloromethyl)quinoline
CAS: 4377-41-7
Molecular Formula: C10H8ClN
2-quinolinylmethyl chloride - Names and Identifiers
| Name | 2-(Chloromethyl)quinoline |
| Synonyms | NSC 158442 alpha-Chloroquinaldine 2-Chloromethylquinoline 2-(chloromethyl)quinoline 2-(Chloromethyl)quinoline 2-quinolinylmethyl chloride Quinoline, 2-(chloromethyl)- |
| CAS | 4377-41-7 |
| EINECS | 224-479-2 |
| InChI | InChI=1/C10H8ClN/c11-7-9-6-5-8-3-1-2-4-10(8)12-9/h1-6H,7H2 |
2-quinolinylmethyl chloride - Physico-chemical Properties
| Molecular Formula | C10H8ClN |
| Molar Mass | 177.63 |
| Density | 1.229±0.06 g/cm3(Predicted) |
| Melting Point | 56.5-57.5℃ |
| Boling Point | 288.8±15.0 °C(Predicted) |
| pKa | 3.48±0.48(Predicted) |
| Storage Condition | 2-8°C |
2-quinolinylmethyl chloride - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
2-quinolinylmethyl chloride - Introduction
2-(Chloromethyl)quinoline is an organic compound with the chemical formula C11H8ClN. It is a yellow to orange crystalline solid, soluble in organic solvents such as ethanol and dichloromethane.
2-(Chloromethyl)quinoline is widely used in organic synthesis. As an active reagent, it can be used to synthesize other organic compounds, such as coordination compounds, biologically active substances and drugs. It has potential applications in the field of medicine, such as the development of anti-cancer drugs and antiviral drugs.
2-(Chloromethyl)quinoline can be prepared by a variety of methods. A common method is to generate 2-(Chloromethyl)quinoline by nucleophilic substitution reaction under base catalysis by reacting quinoline with methyl chloride. The reaction conditions can be adjusted according to the specific situation.
Regarding safety information, 2-(Chloromethyl)quinoline is an organic compound and is potentially dangerous. It can cause irritation and damage to the skin, eyes and respiratory system. Wear appropriate protective equipment such as gloves, goggles, and respiratory protectors when touching or inhaling 2-(Chloromethyl)quinoline. In addition, it should be stored in a cool, well-ventilated place, away from fire and oxidizing agents. If necessary, dispose of waste using appropriate measures. Observe safety practices when using and handling 2-(Chloromethyl)quinoline.
2-(Chloromethyl)quinoline is widely used in organic synthesis. As an active reagent, it can be used to synthesize other organic compounds, such as coordination compounds, biologically active substances and drugs. It has potential applications in the field of medicine, such as the development of anti-cancer drugs and antiviral drugs.
2-(Chloromethyl)quinoline can be prepared by a variety of methods. A common method is to generate 2-(Chloromethyl)quinoline by nucleophilic substitution reaction under base catalysis by reacting quinoline with methyl chloride. The reaction conditions can be adjusted according to the specific situation.
Regarding safety information, 2-(Chloromethyl)quinoline is an organic compound and is potentially dangerous. It can cause irritation and damage to the skin, eyes and respiratory system. Wear appropriate protective equipment such as gloves, goggles, and respiratory protectors when touching or inhaling 2-(Chloromethyl)quinoline. In addition, it should be stored in a cool, well-ventilated place, away from fire and oxidizing agents. If necessary, dispose of waste using appropriate measures. Observe safety practices when using and handling 2-(Chloromethyl)quinoline.
Last Update：2024-04-09 20:52:54
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